Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22680593 | 0.67 | CA1 (0.39) | CA1CA2 | |
| SCHEMBL17624749 | 0.67 | CA1 (0.39) | CA1CA2ALDH1A1 | |
| SCHEMBL3759349 | 0.61 | CA1 (0.46) | CA1CA2ALDH1A1 | |
| SCHEMBL7355622 | 0.60 | ALDH1A1 (0.41) | CA1CA2ALDH1A1 | |
| SCHEMBL3940930 | 0.58 | — | — | |
| SCHEMBL5572071 | 0.58 | — | — | |
| SCHEMBL5758981 | 0.57 | ALDH1A1 (0.60) | CA1CA2ALDH1A1 | |
| SCHEMBL23047985 | 0.55 | CA1 (0.34) | CA1CA2 | |
| SCHEMBL23804919 | 0.55 | CA1 (0.42) | CA1CA2ALDH1A1 | |
| SCHEMBL18463631 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083583-B1 | HETEROCYCLIC MODULATORS OF LIPID SYNTHESIS AND COMBINATIONS THEREOF | SAGIMET BIOSCIENCES INC (US) | 2020-11-18 | — | — | EP | disclosed |