Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3759349 | 0.78 | CA1 (0.46) | ALDH1A1CA1CA2HPGD | |
| SCHEMBL3940930 | 0.69 | — | — | |
| SCHEMBL5572071 | 0.69 | — | — | |
| SCHEMBL7355629 | 0.63 | ALDH1A1 (0.67) | ALDH1A1CA1CA2HPGD | |
| SCHEMBL17624749 | 0.62 | CA1 (0.39) | ALDH1A1CA1CA2HPGD | |
| SCHEMBL7351478 | 0.62 | CA1 (0.39) | CA1CA2 | |
| SCHEMBL20744203 | 0.60 | CA1 (0.42) | ALDH1A1CA1CA2HPGD | |
| SCHEMBL11033708 | 0.59 | ALDH1A1 (1.00) | ALDH1A1CA1CA2 | |
| SCHEMBL7361023 | 0.59 | — | — | |
| SCHEMBL41866 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700383-B1 | NOVEL 1-PHENYLALKANONE 5-HT 4? RECEPTOR LIGANDS | SYNTEX INC (US) | 1998-09-23 | — | — | EP | disclosed |
| WO-1994027965-A1 | NOVEL 1-PHENYLALKANONE 5-HT4 RECEPTOR LIGANDS | SYNTEX (U.S.A.) INC. (US) | 1994-12-08 | — | — | WO | disclosed |