Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD274 | Q9NZQ7 | 6/20 | 0.47 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.44 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22681677 | 0.84 | CD274 (0.44) | CD274PDCD1KDM4CAPPBACE1 | |
| SCHEMBL22681889 | 0.80 | CD274 (0.42) | CD274PDCD1KDM4CKCNH2CTNNB1 | |
| SCHEMBL22681857 | 0.77 | KDM4C (0.41) | CD274KDM4CAPPBACE1KCNH2 | |
| SCHEMBL15839863 | 0.76 | TAAR1 (0.42) | KDM4CKCNH2 | |
| SCHEMBL22681574 | 0.76 | KCNH2 (0.43) | CD274KDM4CKCNH2CTNNB1WNT3A | |
| SCHEMBL19018409 | 0.74 | KCNH2 (0.35) | CD274PDCD1KCNH2 | |
| SCHEMBL22681721 | 0.74 | MEN1 (0.44) | CD274PDCD1KDM4CAPPKCNH2 | |
| SCHEMBL22681646 | 0.74 | AXL (0.47) | CD274PDCD1KDM4CKCNH2 | |
| SCHEMBL22681657 | 0.74 | CTNNB1 (0.45) | KDM4CBACE1KCNH2CTNNB1WNT3A | |
| SCHEMBL22682013 | 0.74 | CTNNB1 (0.53) | KDM4CKCNH2CTNNB1WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160952-B1 | HISTONE DEMETHYLASE INHIBITORS | CELGENE QUANTICEL RES INC (US) | 2020-12-02 | — | — | EP | disclosed |
| EP-3741749-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-25 | — | — | EP | disclosed |
| EP-3738960-A1 | HISTONE DEMETHYLASE INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-11-18 | — | — | EP | disclosed |