Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.50 |
| ▸ | OGA | O60502 | 5/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720576 | 0.88 | SRD5A1 (0.52) | SRD5A1OGASRD5A2HDAC2LSS | |
| SCHEMBL14720706 | 0.84 | SRD5A1 (0.51) | SRD5A1OGASRD5A2HDAC2LSS | |
| SCHEMBL14722165 | 0.84 | SRD5A1 (0.51) | SRD5A1OGASRD5A2HDAC2LSS | |
| SCHEMBL18992022 | 0.80 | OGA (0.45) | SRD5A1OGASRD5A2HDAC2CYP4F2 | |
| SCHEMBL14720788 | 0.78 | SRD5A2 (0.48) | SRD5A1SRD5A2 | |
| SCHEMBL19994676 | 0.78 | SRD5A2 (0.48) | SRD5A1OGASRD5A2 | |
| SCHEMBL17750085 | 0.78 | LSS (0.51) | SRD5A1SRD5A2LSS | |
| SCHEMBL14722734 | 0.78 | OGA (0.52) | SRD5A1OGASRD5A2CYP4F2CYP4A11 | |
| SCHEMBL14722320 | 0.76 | SRD5A1 (0.42) | SRD5A1OGASRD5A2 | |
| SCHEMBL14720404 | 0.75 | ALDH1A1 (0.46) | SRD5A1SRD5A2HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3389658-B1 | GLYCOSIDASE INHIBITORS AND USES THEREOF | MERCK SHARP & DOHME (US) | 2020-11-25 | — | — | EP | disclosed |