Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 4/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720576 | 0.86 | SRD5A1 (0.52) | SRD5A1SRD5A2HDAC2MCHR1OGA | |
| SCHEMBL14722165 | 0.85 | SRD5A1 (0.51) | SRD5A1SRD5A2HDAC2MCHR1OGA | |
| SCHEMBL22683282 | 0.84 | SRD5A1 (0.50) | SRD5A1SRD5A2HDAC2OGALSS | |
| SCHEMBL14720788 | 0.83 | SRD5A2 (0.48) | SRD5A1SRD5A2MCHR1 | |
| SCHEMBL14720589 | 0.80 | GRM5 (0.43) | SRD5A1SRD5A2HDAC2OGA | |
| SCHEMBL19994676 | 0.80 | SRD5A2 (0.48) | SRD5A1SRD5A2OGA | |
| SCHEMBL17750085 | 0.80 | LSS (0.51) | SRD5A1SRD5A2LSS | |
| SCHEMBL14720404 | 0.76 | ALDH1A1 (0.46) | SRD5A1SRD5A2HDAC2 | |
| SCHEMBL4980296 | 0.76 | SRD5A2 (0.48) | SRD5A1SRD5A2 | |
| SCHEMBL28098574 | 0.75 | GSK3B (0.51) | SRD5A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027001-A1 | COMPOUNDS AND THEIR USE TO TREAT HISTAMINE H3 RELATED DISORDERS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2013-02-28 | — | — | WO | disclosed |