Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 9/20 | 0.40 |
| ▸ | IDO1 | P14902 | 7/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | MAST3 | O60307 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686805 | 0.91 | PTGER4 (0.42) | PDE2AIDO1PTGER4PTGDRMAPK8 | |
| SCHEMBL22684799 | 0.84 | IDO1 (0.39) | PDE2AIDO1 | |
| SCHEMBL22685171 | 0.76 | WDR91 (0.43) | PDE2AIDO1PTGER4PTGDR | |
| SCHEMBL22685325 | 0.76 | PDE2A (0.39) | PDE2AIDO1PTGER4PTGDR | |
| SCHEMBL22685191 | 0.75 | WDR91 (0.43) | PDE2AIDO1 | |
| SCHEMBL22685266 | 0.74 | PDE2A (0.40) | PDE2AIDO1HSD17B13 | |
| SCHEMBL22685074 | 0.74 | IDO1 (0.51) | PDE2AIDO1 | |
| SCHEMBL22684761 | 0.74 | HDAC1 (0.44) | IDO1MAST3MAPK8HSD17B13 | |
| SCHEMBL22685327 | 0.73 | PDE2A (0.39) | PDE2AIDO1 | |
| SCHEMBL23919028 | 0.72 | IDO1 (0.60) | PDE2AIDO1HSD17B13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |