Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR91 | A4D1P6 | 7/20 | 0.43 |
| ▸ | PDE2A | O00408 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 4/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 2/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22685351 | 0.91 | WDR91 (0.54) | WDR91PDE2AIDO1 | |
| SCHEMBL22684799 | 0.91 | IDO1 (0.39) | PDE2AIDO1CYP2C9HTR1AABL1 | |
| SCHEMBL22684822 | 0.89 | WDR91 (0.40) | WDR91PDE2AIDO1CYP2C9ABL1 | |
| SCHEMBL22685244 | 0.85 | WDR91 (0.40) | WDR91PDE2AIDO1ABL1KCNH2 | |
| SCHEMBL22685074 | 0.83 | IDO1 (0.51) | WDR91PDE2AIDO1CYP2C9ABL1 | |
| SCHEMBL22685173 | 0.80 | IDO1 (0.42) | WDR91PDE2AIDO1 | |
| SCHEMBL22685330 | 0.80 | CXCR3 (0.42) | PDE2A | |
| SCHEMBL22439026 | 0.78 | IDO1 (0.66) | WDR91PDE2AIDO1CYP2C9 | |
| SCHEMBL22685327 | 0.77 | PDE2A (0.39) | PDE2AIDO1 | |
| SCHEMBL22685192 | 0.75 | PDE2A (0.40) | PDE2AIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |