Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 14/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686808 | 0.92 | PDE2A (0.46) | PDE2ASCN9A | |
| SCHEMBL22686806 | 0.91 | PDE2A (0.49) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684811 | 0.90 | WDR91 (0.41) | PDE2ATRPA1 | |
| SCHEMBL22685187 | 0.87 | PDE2A (0.44) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685184 | 0.86 | PDE2A (0.41) | PDE2ATRPA1HDAC3HDAC1HDAC2 | |
| SCHEMBL22685203 | 0.83 | PDE2A (0.47) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684761 | 0.82 | HDAC1 (0.44) | HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22684816 | 0.80 | PDE2A (0.45) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685347 | 0.78 | PDE2A (0.42) | PDE2AHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL22685266 | 0.78 | PDE2A (0.40) | PDE2AHDAC3HDAC1HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |