Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 11/20 | 0.46 |
| ▸ | WDR91 | A4D1P6 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22686804 | 0.92 | PDE2A (0.47) | PDE2ASCN9A | |
| SCHEMBL22686806 | 0.90 | PDE2A (0.49) | PDE2ASCN9ATRPV1 | |
| SCHEMBL22685203 | 0.87 | PDE2A (0.47) | PDE2AAKT1TRPV1 | |
| SCHEMBL22685187 | 0.86 | PDE2A (0.44) | PDE2ATRPV1 | |
| SCHEMBL22686817 | 0.86 | PDE2A (0.46) | PDE2AWDR91IDO1MALT1TRPV1 | |
| SCHEMBL22685184 | 0.85 | PDE2A (0.41) | PDE2ASCN9ATRPV1 | |
| SCHEMBL22685183 | 0.84 | MALT1 (0.44) | WDR91MALT1AKT1 | |
| SCHEMBL22685345 | 0.84 | PDE2A (0.44) | PDE2AWDR91MALT1AKT1 | |
| SCHEMBL22657408 | 0.82 | MALT1 (0.45) | PDE2AWDR91MALT1AKT1TRPV1 | |
| SCHEMBL22685246 | 0.82 | WDR91 (0.45) | WDR91MALT1AKT1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020228823-A1 | NOVEL AMIDE COMPOUNDS AND USES THEREOF | HUTCHISON MEDIPHARMA LIMITED (CN) | 2020-11-19 | — | — | WO | disclosed |