Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 7/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26630547 | 0.98 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL22639458 | 0.86 | L3MBTL3 (0.42) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| Hydrochloric Acid SCHEMBL27218548 | 0.84 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| Hydrochloric Acid SCHEMBL27218545 | 0.84 | L3MBTL3 (0.41) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL19312856 | 0.83 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1KDM4ETDP1MBTD1 | |
| SCHEMBL27220553 | 0.83 | KDM4E (0.35) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL24782761 | 0.83 | HTR6 (0.54) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL21057384 | 0.83 | HTR6 (0.54) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL22216666 | 0.83 | HTR6 (0.54) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 | |
| SCHEMBL1828721 | 0.83 | HTR6 (0.54) | L3MBTL3L3MBTL1HTR6SLC18A3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022111449-A1 | PREPARATION METHOD FOR BTK DEGRADATION AGENT | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | claimed |
| WO-2022111448-A1 | METHOD FOR PREPARING BTK DEGRADING AGENT | 四川海思科制药有限公司 | 2022-06-02 | — | — | WO | claimed |
| WO-2020232625-A1 | PROCESS OF PREPARING DIAZOMETHANE | 凯莱英医药集团（天津）股份有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |