SCHEMBL22689504

SCHEMBL22689504

C=CCc1ccc2c(c1)OC(OC)O2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.50
MAPT P10636 3/20 0.50
CYP1A2 P05177 1/20 0.50
ALDH1A1 P00352 6/20 0.47
PPARG P37231 2/20 0.47
PPARD Q03181 2/20 0.47
PPARA Q07869 2/20 0.47
ALOX5 P09917 4/20 0.44
PTGS1 P23219 2/20 0.44
AR P10275 1/20 0.44
TRPM8 Q7Z2W7 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.43
TP53 P04637 1/20 0.43
ALOX15 P16050 1/20 0.43
TSHR P16473 1/20 0.43
ALOX12 P18054 1/20 0.43
GABRA1 P14867 4/20 0.40
GABRB2 P47870 4/20 0.40
XDH P47989 1/20 0.40
MEN1 O00255 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5365421 0.84 CYP3A4 (0.47) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL28732003 0.81 CYP3A4 (0.54) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL29417374 0.78 MAPT (0.54) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL14482495 0.76 ALDH1A1 (0.58) CYP3A4MAPTALDH1A1PPARGPPARD
SCHEMBL1292020 0.75 CYP3A4 (0.47) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL31289352 0.73 MAPT (0.49) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL14482492 0.71 CYP3A4 (0.50) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL25694376 0.70 CYP3A4 (0.58) CYP3A4MAPTCYP1A2ALDH1A1PPARG
SCHEMBL10054032 0.70 USP2 (0.37) CYP3A4ALDH1A1KMT2AGAA
SCHEMBL30367930 0.69 CYP3A4 (0.51) CYP3A4MAPTCYP1A2ALDH1A1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250339631-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL STORED OVER TIME SYQE MEDICAL LTD. (IL) 2025-11-06 US disclosed
US-20250157614-A1 SUBSTANCE DELIVERY PLANNING SYSTEM SYQE MEDICAL LTD. (IL) 2025-05-15 US disclosed
EP-4504308-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL STORED OVER TIME Syqe Medical Ltd. (IL) 2025-02-12 EP disclosed
US-20240108577-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL SYQE MEDICAL LTD. (IL) 2024-04-04 US disclosed
WO-2023195007-A1 CONTROLLED RELEASE OF SUBSTANCES FROM A SOURCE MATERIAL STORED OVER TIME SYQE MEDICAL LTD. (IL) 2023-10-12 WO disclosed
US-20220223247-A1 SUBSTANCE DELIVERY PLANNING SYSTEM SYQE MEDICAL LTD. (IL) 2022-07-14 US disclosed
EP-3972551-A1 SUBSTANCE DELIVERY PLANNING SYSTEM Syqe Medical Ltd. (IL) 2022-03-30 EP disclosed
WO-2020234883-A1 SUBSTANCE DELIVERY PLANNING SYSTEM SYQE MEDICAL LTD. (IL) 2020-11-26 WO disclosed