Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1292044 | 0.85 | PTGS2 (0.38) | CYP3A4CYP1A2ALDH1A1MEN1KMT2A | |
| SCHEMBL1291722 | 0.80 | PTGS2 (0.35) | CYP3A4PTGS1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL1291723 | 0.80 | PTGS2 (0.35) | CYP3A4PTGS1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL1291721 | 0.80 | PTGS2 (0.35) | CYP3A4PTGS1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL19005894 | 0.80 | PTGS2 (0.35) | CYP3A4PTGS1ALDH1A1GABRA1GABRB2 | |
| SCHEMBL28732003 | 0.79 | CYP3A4 (0.54) | CYP3A4MAPTCYP1A2PTGS1ALOX5 | |
| SCHEMBL1291782 | 0.78 | PTGS2 (0.40) | CYP3A4PTGS1ALDH1A1HPGDCNR1 | |
| SCHEMBL29852250 | 0.78 | PTGS2 (0.40) | CYP3A4PTGS1ALDH1A1HPGDCNR1 | |
| SCHEMBL31289352 | 0.77 | MAPT (0.49) | CYP3A4MAPTCYP1A2PTGS1ALOX5 | |
| SCHEMBL29417374 | 0.76 | MAPT (0.54) | CYP3A4MAPTCYP1A2PTGS1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| EP-2624811-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | Firmenich SA (CH) | 2013-08-14 | — | — | EP | disclosed |
| WO-2012045646-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | TRPA1, BBOX1, PAOX | CYP3A4 194/4885MAPT 3610/4885CYP1A2 92/4885 |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | BBOX1, CBR3, CBR1 | CYP3A4 131/4885MAPT 2550/4885CYP1A2 68/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.