Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.36 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22689594 | 0.81 | NPC1 (0.36) | TYRCTRCMAPTMEN1KMT2A | |
| SCHEMBL9719205 | 0.80 | MEN1 (0.37) | TLR8MAPTMEN1ALOX5KMT2A | |
| SCHEMBL10475866 | 0.78 | PTGS2 (0.35) | TYRCTRCTLR8PTGS2 | |
| SCHEMBL1771627 | 0.78 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL22981635 | 0.77 | NPC1 (0.36) | TYRTLR8MAPTMEN1TP53 | |
| SCHEMBL23457015 | 0.76 | MAPT (0.36) | TYRMAPTMEN1TP53CYP3A4 | |
| SCHEMBL22689600 | 0.76 | MAPT (0.36) | TYRMAPTMEN1TP53CYP3A4 | |
| SCHEMBL22689640 | 0.76 | MAPT (0.36) | TYRMAPTMEN1TP53CYP3A4 | |
| SCHEMBL23456997 | 0.76 | MAPT (0.36) | TYRMAPTMEN1TP53CYP3A4 | |
| SCHEMBL22689593 | 0.76 | MAPT (0.36) | TYRMAPTMEN1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485605-B2 | Lubricant and fuel compositions containing 2-(S(N)-mercaptobenzothiazole)succinic and methylene succinate esters | CROMPTON CORPORATION (US) | 2009-02-03 | — | — | US | disclosed |
| US-20060089271-A1 | Lubricant and fuel compositions containing 2-(S(N)-mercaptobenzothiazole)succinic and methylene succinate esters | CHEMTURA CORPORATION | 2006-04-27 | — | — | US | disclosed |