Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.66 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.66 |
| ▸ | ITGAV | P06756 | 6/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130791 | 0.99 | ITGB3 (0.65) | ITGB3ITGA2BITGAVACEFOLH1 | |
| SCHEMBL5579946 | 0.99 | ITGB3 (0.65) | ITGB3ITGA2BITGAVACEFOLH1 | |
| SCHEMBL29557195 | 0.93 | ITGB3 (0.58) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL29400646 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL28703518 | 0.92 | ITGB3 (0.57) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL19125526 | 0.90 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL13324009 | 0.88 | ITGB3 (0.55) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL14077189 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL13323977 | 0.86 | ITGB3 (0.53) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL21994894 | 0.85 | ITGB3 (0.61) | ITGB3ITGA2BITGAVACEFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3972605-A1 | A NOVEL THERAPY FOR ERYTHROPOIETIC PROTOPORPHYRIA (EPP) AND X-LINKED PROTOPORPHYRIA (XLP) | University of Pittsburgh - of the Commonwealth System of Higher Education (US) | 2022-03-30 | — | — | EP | disclosed |
| CN-114096250-A | Novel therapy for erythropoietic protoporphyrinopathy (EPP) and X-linked protoporphyrinopathy (XLP) | 匹兹堡大学联邦高等教育系统 | 2022-02-25 | — | — | CN | disclosed |
| WO-2020236901-A1 | A NOVEL THERAPY FOR ERYTHROPOIETIC PROTOPORPHYRIA (EPP) AND X-LINKED PROTOPORPHYRIA (XLP) | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-11-26 | — | — | WO | disclosed |