Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.65 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.65 |
| ▸ | ITGAV | P06756 | 6/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5130791 | 1.00 | ITGB3 (0.65) | ITGB3ITGA2BITGAVACEFOLH1 | |
| SCHEMBL22689909 | 0.99 | ITGB3 (0.66) | ITGB3ITGA2BITGAVACEFOLH1 | |
| SCHEMBL29400646 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL28703518 | 0.93 | ITGB3 (0.57) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL29557195 | 0.92 | ITGB3 (0.58) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL13324009 | 0.89 | ITGB3 (0.55) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL19125526 | 0.89 | ITGB3 (0.66) | ITGB3ITGA2BITGAV | |
| SCHEMBL14077189 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL13323977 | 0.87 | ITGB3 (0.53) | ITGB3ITGA2BITGAVACE | |
| SCHEMBL13324031 | 0.85 | ITGB3 (0.51) | ITGB3ITGA2BITGAVACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7294642-B2 | 1,3-Diamino-2-hydroxypropane pro-drug derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-11-13 | — | — | US | claimed |