Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2227168 | 0.88 | S1PR1 (0.52) | S1PR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL2223895 | 0.86 | S1PR1 (0.52) | S1PR1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2224653 | 0.86 | S1PR1 (0.56) | S1PR1CYP1A2MAPTCYP2C9CYP2C19 | |
| SCHEMBL2225909 | 0.86 | S1PR1 (0.54) | S1PR1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2223341 | 0.86 | S1PR1 (0.54) | S1PR1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2224650 | 0.86 | S1PR1 (0.58) | S1PR1MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL2222853 | 0.86 | S1PR1 (0.58) | S1PR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL2224142 | 0.86 | S1PR1 (0.51) | S1PR1HTTMEN1KMT2ACYP1A2 | |
| SCHEMBL2223355 | 0.85 | S1PR1 (0.73) | S1PR1MEN1KMT2ACYP1A2CYP2C9 | |
| SCHEMBL2228933 | 0.85 | S1PR1 (0.58) | S1PR1HTTMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |