Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.41 |
| ▸ | HPGD | P15428 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 9/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 9/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2223355 | 0.88 | S1PR1 (0.73) | S1PR1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2228933 | 0.88 | S1PR1 (0.58) | S1PR1ALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL2226291 | 0.88 | S1PR1 (0.55) | S1PR1MAPT | |
| SCHEMBL2224909 | 0.87 | S1PR1 (0.58) | S1PR1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2269044 | 0.86 | S1PR1 (0.55) | S1PR1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2224272 | 0.86 | S1PR1 (0.55) | S1PR1ALDH1A1KDM4EL3MBTL1RAB9A | |
| SCHEMBL14797011 | 0.85 | S1PR1 (0.82) | S1PR1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL2227168 | 0.84 | S1PR1 (0.52) | S1PR1ALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2223341 | 0.83 | S1PR1 (0.54) | S1PR1ALDH1A1HPGDHSD17B10TP53 | |
| SCHEMBL2223895 | 0.83 | S1PR1 (0.52) | S1PR1ALDH1A1HPGDHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2523962-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI (FR) | 2012-11-21 | — | — | EP | disclosed |
| WO-2011086079-A1 | CARBOXYLIC ACID DERIVATIVES HAVING A 2,5-SUBSTITUTED OXAZOLOPYRIMIDINE RING | SANOFI-AVENTIS (FR) | 2011-07-21 | — | — | WO | disclosed |