Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.48 |
| ▸ | CTSA | P10619 | 1/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740965 | 1.00 | CTSK (0.50) | CTSKCTSSCTSBCYP26A1CTSA | |
| SCHEMBL740964 | 1.00 | CTSK (0.50) | CTSKCTSSCTSBCYP26A1CTSA | |
| SCHEMBL29861162 | 0.89 | CTSS (0.47) | CTSKCTSSCTSBCYP26A1AAK1 | |
| SCHEMBL21459379 | 0.89 | CTSS (0.47) | CTSKCTSSCTSBCYP26A1AAK1 | |
| SCHEMBL21459378 | 0.89 | CTSS (0.47) | CTSKCTSSCTSBCYP26A1AAK1 | |
| SCHEMBL27351850 | 0.89 | CTSS (0.47) | CTSKCTSSCTSBCYP26A1AAK1 | |
| SCHEMBL4838536 | 0.87 | CTSS (0.49) | CTSKCTSSCTSBAAK1ALDH1A1 | |
| SCHEMBL29676847 | 0.87 | CTSS (0.49) | CTSKCTSSCTSBAAK1ALDH1A1 | |
| SCHEMBL4704028 | 0.87 | CTSS (0.49) | CTSKCTSSCTSBAAK1ALDH1A1 | |
| SCHEMBL4838542 | 0.87 | CTSS (0.49) | CTSKCTSSCTSBAAK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561991-A1 | NOVEL HETEROCYCLES AS SPLA2-X INHIBITORS | Cayman Chemical Company, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| WO-2024026290-A1 | NOVEL HETEROCYCLES AS sPLA2-X INHIBITORS | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2024-02-01 | — | — | WO | disclosed |
| WO-2024026290-A1 | NOVEL HETEROCYCLES AS sPLA2-X INHIBITORS | CAYMAN CHEMICAL COMPANY INCORPORATED (US) | 2024-02-01 | — | — | WO | disclosed |
| EP-3972590-A1 | NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES, KIDNEY DISEASE AND DIABETES | Merck Sharp & Dohme Corp. (US) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020236688-A1 | NATRIURETIC PEPTIDE RECEPTOR A AGONISTS USEFUL FOR THE TREATMENT OF CARDIOMETABOLIC DISEASES, KIDNEY DISEASE AND DIABETES | MERCK SHARP & DOHME CORP. (US) | 2020-11-26 | — | — | WO | disclosed |