Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.59 |
| ▸ | RPTOR | Q8N122 | 6/20 | 0.59 |
| ▸ | MLST8 | Q9BVC4 | 6/20 | 0.59 |
| ▸ | MALT1 | Q9UDY8 | 7/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21360395 | 0.90 | MTOR (0.47) | MTORRPTORMLST8MALT1GRM4 | |
| SCHEMBL21360334 | 0.85 | MTOR (0.77) | MTORRPTORMLST8 | |
| SCHEMBL20142791 | 0.84 | MTOR (0.61) | MTORRPTORMLST8CHRM4 | |
| SCHEMBL20142829 | 0.84 | MTOR (0.56) | MTORRPTORMLST8 | |
| SCHEMBL20140999 | 0.82 | MTOR (0.54) | MTORRPTORMLST8 | |
| SCHEMBL21360354 | 0.82 | MTOR (0.77) | MTORRPTORMLST8CHRM4 | |
| SCHEMBL22693124 | 0.82 | MTOR (0.72) | MTORRPTORMLST8 | |
| SCHEMBL22188090 | 0.82 | MTOR (0.48) | MTORRPTORMLST8 | |
| SCHEMBL20149904 | 0.81 | MTOR (0.52) | MTORRPTORMLST8MALT1SMO | |
| SCHEMBL20133577 | 0.81 | MALT1 (0.53) | MTORRPTORMLST8MALT1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | MTOR 1/4885RPTOR 3/4885MLST8 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.