Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5855587 | 0.85 | MEN1 (0.46) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL5855592 | 0.85 | MEN1 (0.46) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL5454169 | 0.84 | MEN1 (0.51) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL5454170 | 0.84 | MEN1 (0.51) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL27713581 | 0.79 | MEN1 (0.50) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL27590408 | 0.77 | MEN1 (0.51) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL11078921 | 0.77 | FBP1 (0.47) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL2245266 | 0.77 | MEN1 (0.60) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL2245263 | 0.77 | MEN1 (0.60) | MEN1KMT2AKDM4EAKR1C3RECQL | |
| SCHEMBL598599 | 0.76 | TSHR (0.50) | MEN1KMT2AKDM4EAKR1C3RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) | 2020-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844050-B2 | Cyclization processes of hydroxyalkenoic acids and products thereof | FASN, ALOX5, HACL2 | MEN1 4649/4885KMT2A 4218/4885KDM4E 4555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.