SCHEMBL22694283

SCHEMBL22694283

Nc1ccc(NC(=O)c2ccc(Oc3ccc(C(=O)Nc4ccc(N)cc4)cc3)cc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.79
MEN1 O00255 1/20 0.79
LMNA P02545 1/20 0.79
PKM P14618 1/20 0.79
APEX1 P27695 1/20 0.79
KMT2A Q03164 1/20 0.79
TDP1 Q9NUW8 1/20 0.79
NPC1 O15118 3/20 0.69
RAB9A P51151 3/20 0.69
TP53 P04637 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
BRAF P15056 4/20 0.68
HDAC1 Q13547 4/20 0.68
HDAC3 O15379 1/20 0.68
HDAC4 P56524 1/20 0.68
HDAC7 Q8WUI4 1/20 0.68
HDAC2 Q92769 1/20 0.68
HDAC10 Q969S8 1/20 0.68
HDAC11 Q96DB2 1/20 0.68
HDAC8 Q9BY41 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22192221 1.00 POLB (0.79) POLBMEN1LMNAPKMAPEX1
SCHEMBL9812466 1.00 POLB (0.79) POLBMEN1LMNAPKMAPEX1
SCHEMBL22444366 1.00 POLB (0.79) POLBMEN1LMNAPKMAPEX1
SCHEMBL8771228 1.00 POLB (0.79) POLBMEN1LMNAPKMAPEX1
SCHEMBL17198004 0.92 POLB (0.67) POLBMEN1LMNAPKMAPEX1
SCHEMBL28850376 0.92 PGR (0.71) POLBMEN1LMNAPKMAPEX1
SCHEMBL11650148 0.92 PGR (0.81) POLBMEN1LMNAPKMAPEX1
SCHEMBL2128727 0.89 POLB (1.00) POLBMEN1LMNAPKMAPEX1
SCHEMBL137276 0.89 POLB (1.00) POLBMEN1LMNAPKMAPEX1
SCHEMBL1353478 0.89 POLB (1.00) POLBMEN1LMNAPKMAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018127-B2 Additive manufacturing of aromatic thermoplastics from photocurable precursor salts VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2024-06-25 US disclosed
US-12018127-B2 Additive manufacturing of aromatic thermoplastics from photocurable precursor salts VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2024-06-25 US disclosed
US-20210115279-A1 ADDITIVE MANUFACTURING OF AROMATIC THERMOPLASTICS FROM PHOTOCURABLE PRECURSOR SALTS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2021-04-22 US disclosed
US-20200369831-A1 ADDITIVE MANUFACTURING OF AROMATIC THERMOPLASTICS FROM PHOTOCURABLE PRECURSOR SALTS VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY 2020-11-26 US disclosed