SCHEMBL22694355

SCHEMBL22694355

C[C@H](c1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1)C(c1ccccc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
CYP3A4 P08684 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
MAPT P10636 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
PTGS2 P35354 1/20 0.39
CHRNB2 P17787 1/20 0.37
CHRNA4 P43681 1/20 0.37
FAAH O00519 3/20 0.37
MGLL Q99685 2/20 0.37
MEN1 O00255 1/20 0.35
CRHBP P24387 1/20 0.35
KMT2A Q03164 1/20 0.35
ATM Q13315 1/20 0.35
CRHR2 Q13324 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20343040 1.00 ALDH1A1 (0.41) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL23073548 0.98 PTGS2 (0.42) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL10628918 0.85 CYP2C19 (0.39) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL14544053 0.85 ALDH1A1 (0.43) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL10118529 0.85 ALDH1A1 (0.43) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL19328622 0.84 NPY5R (0.38) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL19151931 0.84 PTGS2 (0.52) ALDH1A1PTGS2CHRNB2CHRNA4ACP3
SCHEMBL20099084 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL13010631 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2
SCHEMBL13339008 0.82 ALDH1A1 (0.50) ALDH1A1L3MBTL1CYP3A4KDM4ECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3742510-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2020-11-25 EP disclosed