Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.42 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.42 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.42 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220452 | 0.87 | NPC1 (0.59) | HTR2BHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL12035517 | 0.83 | RAB9A (0.49) | HTR2BHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL9192117 | 0.83 | HTR2B (0.49) | HTR2BHTR2AHTR2CNPC1RAB9A | |
| SCHEMBL9720636 | 0.79 | LMNA (0.65) | TSHRGAALMNAMAPTALDH1A1 | |
| SCHEMBL22591956 | 0.77 | TDP1 (0.62) | HTR2BHTR2AHTR2CTSHRGAA | |
| SCHEMBL11600442 | 0.75 | TSHR (0.70) | TSHRGAATDP1LMNAPTGDR2 | |
| SCHEMBL27448456 | 0.75 | CCNC (0.50) | HTR2ALMNAMAPTALDH1A1MEN1 | |
| Acetic Acid SCHEMBL28548166 | 0.74 | TDP1 (0.48) | HTR2BHTR2AHTR2CTSHRTDP1 | |
| SCHEMBL4238767 | 0.74 | ABL1 (0.51) | HTR2BHTR2AHTR2CTSHRTDP1 | |
| SCHEMBL1006487 | 0.74 | NPC1 (0.52) | HTR2BHTR2AHTR2CNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233645-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | 浙江海正药业股份有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |