Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL125618 | 0.80 | NCF1 (0.50) | KDM1AALDH1A1NCF1HRH3 | |
| SCHEMBL12561223 | 0.78 | — | — | |
| SCHEMBL26990573 | 0.78 | — | — | |
| SCHEMBL12717742 | 0.76 | KDM1A (0.43) | KDM1AALDH1A1NCF1ALOX15L3MBTL1 | |
| SCHEMBL12561327 | 0.75 | — | — | |
| SCHEMBL27050224 | 0.75 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL17285970 | 0.75 | ALDH1A1 (0.40) | KDM1AALDH1A1NCF1ALOX15L3MBTL1 | |
| SCHEMBL25820276 | 0.75 | KDM1A (0.42) | KDM1AALDH1A1NCF1ALOX15L3MBTL1 | |
| SCHEMBL24092994 | 0.74 | TYK2 (0.34) | — | |
| SCHEMBL30009572 | 0.74 | JAK1 (0.40) | ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974423-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Shanghai Hansoh Biomedical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |
| WO-2020233669-A1 | INDOLE DERIVATIVE-CONTAINING INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |