Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16913924 | 0.82 | PIK3C3 (0.39) | ALDH1A1 | |
| SCHEMBL30481961 | 0.79 | PTK2 (0.40) | ALDH1A1 | |
| SCHEMBL25323093 | 0.79 | PTK2 (0.40) | ALDH1A1 | |
| Water SCHEMBL25321793 | 0.75 | PTK2 (0.37) | ALDH1A1 | |
| SCHEMBL20704188 | 0.74 | CHRNB2 (0.32) | ALDH1A1 | |
| SCHEMBL31229804 | 0.73 | CHRNB2 (0.31) | ALDH1A1 | |
| SCHEMBL25324652 | 0.72 | PIK3C3 (0.35) | ALDH1A1 | |
| SCHEMBL16926689 | 0.72 | PIK3C3 (0.49) | ALDH1A1 | |
| SCHEMBL20203264 | 0.69 | — | — | |
| SCHEMBL16913805 | 0.69 | PIK3C3 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020237025-A1 | SUBSTITUTED EXO-METHYLENE-OXINDOLES WHICH ARE HPK1/MAP4K1 INHIBITORS | GILEAD SCIENCES, INC. (US) | 2020-11-26 | — | — | WO | disclosed |