Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 14/20 | 0.35 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30481961 | 0.91 | PTK2 (0.40) | PIK3C3PTK2ALDH1A1 | |
| SCHEMBL25323093 | 0.91 | PTK2 (0.40) | PIK3C3PTK2ALDH1A1 | |
| Water SCHEMBL25321793 | 0.87 | PTK2 (0.37) | PIK3C3PTK2ALDH1A1IGF1R | |
| SCHEMBL16913805 | 0.80 | PIK3C3 (0.35) | PIK3C3 | |
| SCHEMBL4014634 | 0.76 | LMNA (0.35) | PIK3C3PTK2ALDH1A1 | |
| SCHEMBL25322065 | 0.75 | — | — | |
| SCHEMBL22695577 | 0.72 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL16913924 | 0.70 | PIK3C3 (0.39) | PIK3C3ALDH1A1 | |
| SCHEMBL16913757 | 0.67 | PIK3C3 (0.56) | PIK3C3ALDH1A1 | |
| SCHEMBL30867441 | 0.66 | POLB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023146990-A1 | COMPOUNDS AND METHODS OF USE | TANGO THERAPEUTICS, INC. (US) | 2023-08-03 | — | — | WO | disclosed |