Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474031 | 0.83 | CA2 (0.41) | KDM4EHSD17B10MAPTSMN1; SMN2KMT2A | |
| SCHEMBL5993835 | 0.82 | HPGD (0.51) | ALDH1A1STSLMNAMAPTHPGD | |
| SCHEMBL965172 | 0.81 | TDP1 (0.55) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL3424473 | 0.79 | TDP1 (0.53) | ALDH1A1LMNAMAPTKMT2A | |
| Hydrochloric Acid SCHEMBL28294563 | 0.79 | TDP1 (0.53) | ALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL15533022 | 0.78 | CA2 (0.56) | ALDH5A1ABATALDH1A1KDM4ESTS | |
| SCHEMBL6204063 | 0.78 | CYP2A6 (0.44) | ALDH5A1ABATALDH1A1KDM4ESTS | |
| SCHEMBL7761754 | 0.78 | PTPN1 (0.36) | LMNAKMT2APTGS2 | |
| SCHEMBL27521554 | 0.78 | TDP1 (0.31) | — | |
| SCHEMBL2265907 | 0.78 | MAOA (0.45) | ALDH1A1KDM4ECYP2A6PTGS2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115960023-B | Method for preparing 3-phenyl-L-serine or derivative thereof and ethyl ester thereof | 苏州引航生物科技有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-115960023-A | Method for preparing 3-phenyl-L-serine or derivative and ethyl ester thereof | 苏州引航生物科技有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-115819299-A | Method for preparing 3-phenyl-L-serine or derivative and ethyl ester thereof | 苏州引航生物科技有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-111377839-B | Method for preparing 3-phenyl-L-serine or derivative and ethyl ester thereof | 苏州引航生物科技有限公司 | 2022-06-17 | — | — | CN | disclosed |
| CN-111377839-A | Method for preparing 3-phenyl-L-serine or derivative and ethyl ester thereof | 苏州引航生物科技有限公司 | 2020-07-07 | — | — | CN | disclosed |
| US-8003649-B2 | Bicyclic derivatives for use in the treatment of androgen receptor associated conditions-155 | ASTRAZENECA AB (SE) | 2011-08-23 | — | — | US | disclosed |
| US-20100016279-A1 | BICYCLIC DERIVATIVES FOR USE IN THE TREATMENT OF ANDROGEN RECEPTOR ASSOCIATED CONDITIONS-155 | ASTRAZENECA AB (SE) | 2010-01-21 | — | — | US | disclosed |
| CN-101006085-A | Substituted hydantoins | HOFFMANN LA ROCHE (CH) | 2007-07-25 | — | — | CN | disclosed |
| CN-1279026-C | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2006-10-11 | — | — | CN | disclosed |
| CN-1261412-C | Indole derivatives as COXII inhibitors | HOFFMANN LA ROCHE (CH) | 2006-06-28 | — | — | CN | disclosed |
| CN-1561334-A | Indole derivatives as COXII inhibitors | HOFFMANN LA ROCHE (CH) | 2005-01-05 | — | — | CN | disclosed |
| CN-1167687-C | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ���Ͽع�����˾ | 2004-09-22 | — | — | CN | disclosed |
| CN-1342149-A | Prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2002-03-27 | — | — | CN | disclosed |
| CN-1277605-A | Arylpyridazinones as prostaglandin endoperoxide H synthase biosynthesis inhibitors | ABBOTT LAB (US) | 2000-12-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016279-A1 | BICYCLIC DERIVATIVES FOR USE IN THE TREATMENT OF ANDROGEN RECEPTOR ASSOCIATED CONDITIONS-155 | AR, NR5A1, CYP17A1 | ALDH5A1 775/4885ABAT 247/4885ALDH1A1 806/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.