⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1617849 | 0.69 | HTR6 (0.32) | — | |
| SCHEMBL18840497 | 0.67 | KDM4E (0.39) | — | |
| SCHEMBL31320527 | 0.66 | NSD1 (0.33) | — | |
| SCHEMBL21261372 | 0.66 | TDP1 (0.40) | — | |
| SCHEMBL31329988 | 0.65 | PDE10A (0.37) | — | |
| SCHEMBL18549500 | 0.65 | TAAR1 (0.32) | — | |
| SCHEMBL28260907 | 0.64 | POLB (0.44) | — | |
| Hydrochloric Acid SCHEMBL21752277 | 0.64 | TAAR1 (0.31) | — | |
| SCHEMBL20681213 | 0.64 | GAA (0.34) | — | |
| SCHEMBL31323184 | 0.64 | KDM4E (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240158390-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | JANSSEN SCIENCES IRELAND UNLMITED COMPANY (IE) | 2024-05-16 | — | — | US | disclosed |
| EP-3972964-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2022-03-30 | — | — | EP | disclosed |
| CN-113874380-A | Other heteroaromatic compounds with anti-RSV activity | 爱尔兰詹森科学公司 | 2021-12-31 | — | — | CN | disclosed |
| WO-2020234333-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-26 | — | — | WO | disclosed |
| WO-2020234333-A1 | OTHER HETEROAROMATIC COMPOUNDS HAVING ACTIVITY AGAINST RSV | Janssen Sciences Ireland Unlimited Company (IE) | 2020-11-26 | — | — | WO | disclosed |