Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.72 |
| ▸ | MAPT | P10636 | 3/20 | 0.72 |
| ▸ | TSHR | P16473 | 3/20 | 0.72 |
| ▸ | BLM | P54132 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.72 |
| ▸ | RGS12 | O14924 | 2/20 | 0.72 |
| ▸ | GMNN | O75496 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 2/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | HPGD | P15428 | 2/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.72 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.72 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.72 |
| ▸ | THPO | P40225 | 2/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13941361 | 1.00 | SMN1; SMN2 (0.72) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL10144266 | 0.89 | IGF1R (0.76) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL26214345 | 0.86 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| Tyrphostin A9 SCHEMBL120440 | 0.84 | MEN1 (1.00) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL25736022 | 0.80 | MEN1 (0.78) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL7175613 | 0.79 | SMN1; SMN2 (0.61) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL13051195 | 0.77 | EGFR (0.64) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| Tyrphostin Ag 879 SCHEMBL607701 | 0.77 | MAPT (1.00) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| Tyrphostin Ag 879 SCHEMBL607702 | 0.77 | MAPT (1.00) | SMN1; SMN2MEN1CYP3A4MAPTTSHR | |
| SCHEMBL8346188 | 0.77 | EGFR (0.76) | SMN1; SMN2MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |