Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MITF | O75030 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17466928 | 0.81 | ALDH1A1 (0.54) | TP53TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL5854212 | 0.81 | TP53 (0.56) | TP53TDP1ALDH1A1MAPTPTGS2 | |
| SCHEMBL26552237 | 0.80 | GABRA1 (0.51) | TP53TDP1GABRA1GABRG2GABRB3 | |
| SCHEMBL26552233 | 0.79 | MAPT (0.54) | MAPTMAPK1NPC1RAB9APTGS2 | |
| SCHEMBL762892 | 0.77 | MCL1 (0.50) | GABRA1GABRG2GABRB3KDM4EALDH1A1 | |
| SCHEMBL679854 | 0.77 | MCL1 (0.50) | GABRA1GABRG2GABRB3KDM4EALDH1A1 | |
| SCHEMBL5168254 | 0.77 | MCL1 (0.50) | GABRA1GABRG2GABRB3KDM4EALDH1A1 | |
| SCHEMBL23192677 | 0.76 | MAPT (0.58) | TP53TDP1KDM4EALDH1A1MAPT | |
| SCHEMBL26447187 | 0.76 | MAPT (0.39) | GABRA1GABRG2GABRB3KDM4EALDH1A1 | |
| SCHEMBL26447174 | 0.76 | GABRA1 (0.38) | GABRA1GABRG2GABRB3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3172272-B1 | MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION | MILLIKEN & CO (US) | 2020-11-25 | — | — | EP | disclosed |