Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12019238 | 0.88 | KMT2A (0.48) | KMT2AEPHX1PSMB5TRPA1SMN1; SMN2 | |
| SCHEMBL15580639 | 0.82 | OPRM1 (0.48) | OPRM1KMT2AEPHX1TRPA1SMN1; SMN2 | |
| SCHEMBL15200265 | 0.82 | OPRM1 (0.48) | OPRM1KMT2AEPHX1TRPA1SMN1; SMN2 | |
| SCHEMBL687030 | 0.82 | OPRM1 (0.48) | OPRM1KMT2AEPHX1TRPA1SMN1; SMN2 | |
| SCHEMBL2576766 | 0.81 | KMT2A (0.44) | KMT2APSMB5TRPA1SMN1; SMN2HSD17B10 | |
| SCHEMBL2576767 | 0.81 | KMT2A (0.44) | KMT2APSMB5TRPA1SMN1; SMN2HSD17B10 | |
| SCHEMBL12508317 | 0.81 | PSMB5 (0.44) | KMT2AEPHX1PSMB5TRPA1SMN1; SMN2 | |
| SCHEMBL23221254 | 0.79 | OPRM1 (0.43) | OPRM1KMT2AEPHX1TRPA1SMN1; SMN2 | |
| SCHEMBL13574437 | 0.79 | KMT2A (0.41) | KMT2AEPHX1PSMB5TRPA1SMN1; SMN2 | |
| SCHEMBL21728758 | 0.79 | OPRM1 (0.43) | OPRM1KMT2AEPHX1TRPA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236808-A1 | METHODS FOR PREPARING PSMA CONJUGATES | ENDOCYTE, INC. (US) | 2020-11-26 | — | — | WO | disclosed |