Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | STAT6 | P42226 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31042237 | 0.87 | GAA (0.47) | GAAMAPK1TSHRPOLBAPEX1 | |
| SCHEMBL7256924 | 0.87 | GAA (0.47) | GAAMAPK1TSHRPOLBAPEX1 | |
| SCHEMBL1364551 | 0.87 | MAPK1 (0.54) | GAAMAPK1TSHRPOLBAPEX1 | |
| SCHEMBL31079411 | 0.87 | MAPK1 (0.54) | GAAMAPK1TSHRPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL9360725 | 0.85 | MAPK1 (0.53) | GAAMAPK1TSHRPOLBAPEX1 | |
| SCHEMBL15352924 | 0.85 | GAA (0.52) | GAAMAPK1TSHRPOLBALDH1A1 | |
| SCHEMBL3285978 | 0.85 | MEN1 (0.49) | GAAMAPK1TSHRPOLBALDH1A1 | |
| SCHEMBL8261355 | 0.85 | SMN1; SMN2 (0.59) | GAAMAPK1TSHRPOLBHTT | |
| SCHEMBL7144405 | 0.83 | GAA (0.65) | GAATSHRPOLBHTTLMNA | |
| SCHEMBL7904015 | 0.83 | HMGCR (0.47) | GAAMAPK1TSHRPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7998981-B2 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES LIMITED (IN) | 2011-08-16 | — | — | US | disclosed |
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | SUVEN LIFE SCIENCES, LTD. (IN) | 2010-07-01 | — | — | US | disclosed |
| EP-1919896-B1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LTD (IN) | 2009-12-23 | — | — | EP | disclosed |
| EP-1919896-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | Suven Life Sciences Limited (IN) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007020652-A1 | AMINOARYL SULPHONAMIDE DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS. | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |
| US-6214882-B1 | Benzenesulphonamide derivatives, preparation thereof and therapeutical uses thereof | SYNTHELABO (FR) | 2001-04-10 | — | — | US | disclosed |
| EP-0842148-B1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SANOFI SYNTHELABO (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0842148-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1998-05-20 | — | — | EP | disclosed |
| WO-1997006136-A1 | BENZENESULPHONAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTICAL USES THEREOF | SYNTHELABO (FR) | 1997-02-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168168-A1 | Aminoaryl sulphonamide derivatives as functional 5-HT6 ligands | HTR6, HTR5A, HTR3B | GAA 3920/4885MAPK1 3885/4885TSHR 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.