Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13227665 | 1.00 | LMNA (0.36) | LMNAGBA1TYRALDH1A1TSHR | |
| SCHEMBL9651142 | 1.00 | LMNA (0.36) | LMNAGBA1TYRALDH1A1TSHR | |
| SCHEMBL13471596 | 0.81 | — | — | |
| SCHEMBL6531931 | 0.77 | LMNA (0.35) | LMNAGBA1 | |
| SCHEMBL26878955 | 0.77 | LMNA (0.35) | LMNAGBA1 | |
| SCHEMBL15947355 | 0.75 | AMY2A (0.31) | — | |
| SCHEMBL12964382 | 0.75 | LMNA (0.32) | LMNAGBA1 | |
| SCHEMBL25867417 | 0.72 | OGA (0.33) | LMNAGBA1 | |
| SCHEMBL26651247 | 0.72 | OGA (0.33) | LMNAGBA1 | |
| SCHEMBL14554121 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020236621-A1 | ASCAROSIDE DERIVATIVES AND METHODS OF USE | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2020-11-26 | — | — | WO | disclosed |