SCHEMBL22698273

SCHEMBL22698273

c1ccc(-c2ccc3oc4cncc(-c5nc(-c6ccccc6)nc(-c6ccccc6)n5)c4c3c2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G2A P14555 3/20 0.38
PLA2G4A P47712 3/20 0.38
GAA P10253 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CDK1 P06493 4/20 0.36
CCNB1 P14635 4/20 0.36
CCNE1 P24864 4/20 0.36
CDK2 P24941 4/20 0.36
GSK3B P49841 4/20 0.36
CCNE2 O96020 3/20 0.36
CDK5 Q00535 3/20 0.36
CDK5R1 Q15078 3/20 0.36
PIM1 P11309 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
PIM3 Q86V86 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
TBK1 Q9UHD2 1/20 0.36
PGR P06401 1/20 0.35
CDK4 P11802 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23947709 0.93 KDM4E (0.40) PLA2G2APLA2G4ACDK1CCNB1CCNE1
SCHEMBL22698440 0.91 MEN1 (0.37) PLA2G2APLA2G4AGAAL3MBTL1CDK1
SCHEMBL22698452 0.91 MEN1 (0.37) PLA2G2APLA2G4AGAAL3MBTL1CDK1
SCHEMBL25508746 0.89 PRKCZ (0.37) PLA2G2APLA2G4AL3MBTL1MEN1KMT2A
SCHEMBL24762270 0.88 PRKCZ (0.35) GAAL3MBTL1CDK1CCNB1CCNE1
SCHEMBL23944458 0.88 PRKCZ (0.35) GAAL3MBTL1CDK1CCNB1CCNE1
SCHEMBL22698398 0.88 L3MBTL1 (0.34) PLA2G2APLA2G4AGAAL3MBTL1CDK1
SCHEMBL23944820 0.88 CYP11B1 (0.38) GAAL3MBTL1PGRMEN1KMT2A
SCHEMBL23944537 0.87 KDM4E (0.39) PGRMEN1KMT2AALDH1A1MAPT
SCHEMBL25505110 0.86 AHR (0.36) PLA2G2APLA2G4AMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019212287-A9 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed