Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6211391 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL22698637 | 0.82 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL3043208 | 0.80 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2ALMNAKDM4E | |
| SCHEMBL4705323 | 0.79 | ALDH1A1 (0.41) | ALDH1A1MAPTKMT2ALMNACYP19A1 | |
| SCHEMBL18396739 | 0.78 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2ALMNAMAPK1 | |
| SCHEMBL4703887 | 0.77 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2ALMNAMEN1 | |
| SCHEMBL22689488 | 0.77 | — | — | |
| SCHEMBL18396719 | 0.77 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2ALMNACYP19A1 | |
| SCHEMBL21690959 | 0.76 | ALDH1A1 (0.38) | ALDH1A1MAPTKMT2ALMNATDP1 | |
| SCHEMBL6209802 | 0.76 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2ALMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234636-A1 | NOVEL COMPOUNDS FOR THE TREATMENT OF MAMMALIAN INFECTIONS | CADILA HEALTHCARE LIMITED (IN) | 2020-11-26 | — | — | WO | disclosed |