Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18396719 | 0.84 | ALDH1A1 (0.38) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4705323 | 0.83 | ALDH1A1 (0.41) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL4703887 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6211391 | 0.82 | ALDH1A1 (0.40) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL22689303 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL22698549 | 0.80 | ALDH1A1 (0.35) | ALDH1A1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL240096 | 0.79 | MAPT (0.43) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL6478813 | 0.79 | ALDH1A1 (0.38) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL22698610 | 0.79 | ALDH1A1 (0.34) | ALDH1A1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL31640059 | 0.78 | HTT (0.53) | ALDH1A1KMT2ANPC1RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549641-A1 | ANTIMICROBIAL 3.1.0 BICYCLIC OXAZOLIDINONE DERIVATIVES | Pharmacia & Upjohn Company LLC (US) | 2005-07-06 | — | — | EP | disclosed |
| US-6875784-B2 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2005-04-05 | — | — | US | disclosed |
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-01 | — | — | US | disclosed |
| WO-2004033451-A1 | ANTIMICROBIAL [3.1.0] BICYCLIC OXAZOLIDINONE DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127530-A1 | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives | OXA1L, CYP1B1, MT-CO1 | ALDH1A1 345/4885KMT2A 3114/4885NPC1 2062/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.