Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 5/20 | 0.44 |
| ▸ | NT5E | P21589 | 14/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19974417 | 0.81 | PDE2A (0.51) | PDE2ANT5E | |
| SCHEMBL19979260 | 0.79 | PDE2A (0.49) | PDE2ANT5EPDE4D | |
| SCHEMBL22700162 | 0.77 | PDE2A (0.46) | PDE2ANT5E | |
| SCHEMBL19974448 | 0.72 | ADORA2A (0.55) | PDE2ANT5EPDE4D | |
| SCHEMBL19974411 | 0.71 | PDE2A (0.46) | PDE2ANT5E | |
| SCHEMBL22700332 | 0.69 | PDE2A (0.57) | PDE2ANT5EPDE4D | |
| SCHEMBL22700164 | 0.67 | PDE2A (0.52) | PDE2ANT5E | |
| SCHEMBL4757814 | 0.66 | ADORA3 (0.56) | PDE2ANT5EPDE4D | |
| SCHEMBL22700414 | 0.65 | NT5E (0.44) | NT5EPDE4D | |
| SCHEMBL2060472 | 0.65 | PDE4A (0.67) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |