Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 4/20 | 0.46 |
| ▸ | NT5E | P21589 | 15/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22700164 | 0.89 | PDE2A (0.52) | PDE2ANT5EADORA3 | |
| SCHEMBL19974411 | 0.88 | PDE2A (0.46) | PDE2ANT5EADORA3 | |
| SCHEMBL19979260 | 0.87 | PDE2A (0.49) | PDE2ANT5EADORA3 | |
| SCHEMBL22700179 | 0.87 | NT5E (0.43) | NT5EADORA3 | |
| SCHEMBL19978932 | 0.80 | PDE2A (0.49) | PDE2ANT5EADORA3 | |
| SCHEMBL22700147 | 0.79 | PDE2A (0.53) | PDE2ANT5EADORA3 | |
| SCHEMBL19974455 | 0.79 | PDE2A (0.53) | PDE2ANT5EADORA3 | |
| SCHEMBL19974435 | 0.77 | ADORA2A (0.49) | NT5EADORA3 | |
| SCHEMBL22700153 | 0.77 | PDE2A (0.44) | PDE2ANT5E | |
| SCHEMBL22700178 | 0.77 | NT5E (0.50) | NT5EADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |