Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19864859 | 0.81 | — | — | |
| SCHEMBL3478591 | 0.77 | NOS1 (0.35) | NOS1NOS3NOS2 | |
| SCHEMBL22343769 | 0.74 | ADORA1 (0.43) | HRH4 | |
| SCHEMBL14580328 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL20849726 | 0.69 | HPRT1 (0.33) | — | |
| SCHEMBL21303631 | 0.60 | NOS3 (0.32) | NOS1NOS3NOS2 | |
| SCHEMBL821227 | 0.58 | — | — | |
| SCHEMBL10271926 | 0.57 | KDR (0.35) | NOS1NOS3NOS2 | |
| SCHEMBL21772198 | 0.57 | — | — | |
| SCHEMBL21383159 | 0.56 | HPRT1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512860-B1 | NUCLEOSIDE AND NUCLEOTIDE ANALOGUES BEARING A QUATERNARY ALL-CARBON STEREOGENIC CENTER AT THE 2' POSITION AND METHODS OF USE AS A CARDIOPROTECTIVE AGENT | LCB PHARMA INC (CA) | 2020-11-25 | — | — | EP | disclosed |