SCHEMBL22700345

SCHEMBL22700345

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)sc3cccc(-c5nc(-c6ccccc6)nc(-c6ccc7oc8ccccc8c7c6)n5)c34)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.34
PLA2G2A P14555 2/20 0.34
PLA2G4A P47712 2/20 0.34
PLA2G10 O15496 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HPGD P15428 4/20 0.33
MAPT P10636 4/20 0.33
KDM4E B2RXH2 3/20 0.33
KMT2A Q03164 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 2/20 0.33
MEN1 O00255 1/20 0.33
RAB9A P51151 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPK1 P28482 2/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 2/20 0.32
HSD17B10 Q99714 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22329316 1.00 CHEK2 (0.34) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL22700618 0.96 KMT2A (0.38) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL21707328 0.95 CHEK2 (0.35) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL22329314 0.94 AHR (0.34) ALDH1A1HPGDMAPTKDM4EKMT2A
SCHEMBL24264190 0.94 PRKDC (0.34) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL24264114 0.94 PLA2G2A (0.35) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL21756121 0.94 LIMK1 (0.34) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL24264256 0.94 PLA2G2A (0.35) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL22760322 0.94 PLA2G2A (0.37) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1
SCHEMBL26192936 0.94 ALOX5 (0.34) CHEK2PLA2G2APLA2G4APLA2G10HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020235976-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed