SCHEMBL22700419

SCHEMBL22700419

Clc1ccc2c(c1)sc1c(-c3nc(-c4ccccc4)nc(-c4cccc5c4sc4ccccc45)n3)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
NPC1 O15118 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
PDE5A O76074 4/20 0.38
ABCG2 Q9UNQ0 4/20 0.38
PRKDC P78527 1/20 0.38
TOP1 P11387 1/20 0.37
TOP2A P11388 1/20 0.37
KDM4E B2RXH2 1/20 0.37
NR1I3 Q14994 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
PARP14 Q460N5 1/20 0.36
LIMK1 P53667 1/20 0.36
TNKS O95271 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
F9 P00740 1/20 0.36
MAPT P10636 1/20 0.35
CYP1A1 P04798 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20754136 0.97 NPC1 (0.40) ALOX5NPC1MAPK1HTTRAB9A
SCHEMBL24151932 0.91 NR1I3 (0.45) ALOX5MAPK1PDE5AABCG2PRKDC
SCHEMBL22274501 0.91 ALOX5 (0.47) ALOX5NPC1RAB9APDE5AABCG2
SCHEMBL31643199 0.90 ALOX5 (0.44) ALOX5NPC1MAPK1HTTRAB9A
SCHEMBL22700445 0.88 ALOX5 (0.50) ALOX5MAPK1RAB9APRKDCKDM4E
SCHEMBL22329422 0.88 ALOX5 (0.50) ALOX5MAPK1RAB9APRKDCKDM4E
SCHEMBL15501880 0.88 ALOX5 (0.50) ALOX5MAPK1PRKDCKDM4EPARP14
SCHEMBL17232201 0.88 ALOX5 (0.50) ALOX5MAPK1PRKDCKDM4EPARP14
SCHEMBL22700615 0.88 TOP1 (0.35) ALOX5NPC1MAPK1HTTRAB9A
SCHEMBL23024897 0.88 ALOX5 (0.44) ALOX5NPC1RAB9APDE5AABCG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020235976-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 (KR) 2020-11-26 WO disclosed