Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27101330 | 0.92 | SMN1; SMN2 (0.46) | RAB9ASMN1; SMN2NPC1RECQLALDH1A1 | |
| SCHEMBL4237996 | 0.91 | SMN1; SMN2 (0.62) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL10875405 | 0.88 | RAB9A (0.64) | RAB9ASMN1; SMN2NPC1RECQLALDH1A1 | |
| SCHEMBL10895369 | 0.86 | NPC1 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL11138867 | 0.86 | NPC1 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL11133582 | 0.86 | NPC1 (0.58) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPK1 | |
| SCHEMBL11134616 | 0.85 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL764568 | 0.83 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2NPC1RECQLALDH1A1 | |
| SCHEMBL4690673 | 0.83 | POLB (0.61) | RAB9ASMN1; SMN2NPC1ALDH1A1MAPT | |
| SCHEMBL24663651 | 0.83 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2NPC1RECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3433296-B1 | REACTIVE HOT MELT ADHESIVE COMPOSITION | FULLER H B CO (US) | 2020-11-25 | — | — | EP | disclosed |