SCHEMBL2270165

SCHEMBL2270165

CCC[SiH](CCNCC)C(C)CC

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.37
CYP2C19 P33261 2/20 0.33
MEN1 O00255 1/20 0.33
GLA P06280 1/20 0.33
KMT2A Q03164 1/20 0.33
KDM1A O60341 5/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2276021 0.84 TSHR (0.39) TSHRCYP2C19MEN1GLAKMT2A
SCHEMBL15915164 0.81 TSHR (0.32) TSHR
SCHEMBL2276028 0.80 EPHX1 (0.32)
SCHEMBL2272001 0.70
SCHEMBL2102358 0.67
SCHEMBL2266438 0.67 CYP2C19 (0.41) TSHRCYP2C19MEN1GLAKMT2A
SCHEMBL2274021 0.67 DNM1 (0.32)
SCHEMBL15915213 0.66 TSHR (0.33) TSHR
SCHEMBL2101282 0.65 TSHR (0.42) TSHRCYP2C19MEN1GLAKMT2A
SCHEMBL2267458 0.65 TP53 (0.33) KDM1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed