SCHEMBL22702676

SCHEMBL22702676

CC(C)[C@H](NC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(=O)C=CC1=O)C(=O)N[C@@H](C)C(=O)Nc1ccc(CO)cc1

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 1/20 0.38
▸ MGLL Q99685 1/20 0.36
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ HTT P42858 1/20 0.32
▸ SMN1; SMN2 Q16637 2/20 0.32
▸ NPC1 O15118 1/20 0.32
▸ RAB9A P51151 1/20 0.32
▸ HRH1 P35367 5/20 0.31
▸ CASP1 P29466 1/20 0.31
▸ SDCBP O00560 1/20 0.31
▸ SDC2 P34741 1/20 0.31
▸ NAMPT P43490 1/20 0.30
▸ USP2 O75604 1/20 0.30
▸ FNTA P49354 1/20 0.30
▸ FNTB P49356 1/20 0.30
▸ ADAMTS4 O75173 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31045397 1.00 NR3C1 (0.38) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL23071797 1.00 NR3C1 (0.38) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL23680476 0.94 NR3C1 (0.38) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL31045379 0.92 NR3C1 (0.36) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL31045253 0.92 NR3C1 (0.36) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL23846023 0.92 NR3C1 (0.38) NR3C1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL24898123 0.92 NR3C1 (0.38) NR3C1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL23961616 0.92 NR3C1 (0.38) NR3C1MEN1KMT2AHTTSMN1; SMN2
SCHEMBL23432943 0.90 NR3C1 (0.35) NR3C1MGLLMEN1KMT2AHTT
SCHEMBL23071942 0.90 NR3C1 (0.41) NR3C1MEN1KMT2AHTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4673474-A2 ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE Eisai R&D Management Co., Ltd. (JP) 2026-01-07 — — EP disclosed
WO-2024182569-A2 ANTI-PSMA ANTIBODIES, CONJUGATES, AND METHODS OF USE EISAI R&D MANAGEMENT CO., LTD. (JP) 2024-09-06 — — WO disclosed
US-20200368361-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2020-11-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200368361-A1 RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF ASGR1, CUTA, SRPRA NR3C1 2419/4885MGLL 3034/4885MEN1 2520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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