Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900047 | 0.81 | HRH3 (0.50) | HRH3TAAR1ACHE | |
| SCHEMBL18762839 | 0.77 | HRH3 (0.84) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL19968180 | 0.74 | KDM1A (0.47) | TAAR1ACHE | |
| SCHEMBL24365618 | 0.69 | HRH3 (0.43) | HRH3TAAR1CHRNA7 | |
| SCHEMBL24364832 | 0.69 | HRH3 (0.43) | HRH3TAAR1CHRNA7 | |
| SCHEMBL3057063 | 0.69 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL1975214 | 0.69 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL3059072 | 0.69 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL3046909 | 0.69 | HRH3 (0.70) | HRH3TAAR1CHRNA7KCNH2 | |
| SCHEMBL30551760 | 0.67 | HRH3 (0.41) | HRH3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233138-A1 | USE OF HORDENINE IN PREPARING DRUG FOR TREATING HYPOPHYSOMA | WANG XIONG (CN) | 2020-11-26 | — | — | WO | disclosed |