SCHEMBL3059072

SCHEMBL3059072

CCCc1ccc(CCN(C)C)cc1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.70
TAAR1 Q96RJ0 6/20 0.64
LPL P06858 1/20 0.46
LIPG Q9Y5X9 1/20 0.46
CHRNA7 P36544 1/20 0.45
KCNH2 Q12809 1/20 0.44
AOC3 Q16853 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18762839 0.89 HRH3 (0.84) HRH3TAAR1CHRNA7KCNH2AOC3
SCHEMBL3053110 0.86 HRH3 (0.64) HRH3TAAR1KCNH2
SCHEMBL3057063 0.85 HRH3 (0.70) HRH3TAAR1CHRNA7KCNH2AOC3
SCHEMBL3052389 0.82 TAAR1 (0.63) HRH3TAAR1CHRNA7AOC3
SCHEMBL15935950 0.82 THRA (0.63) HRH3TAAR1LPLLIPGKCNH2
SCHEMBL26456364 0.81 HRH3 (0.64) HRH3TAAR1CHRNA7
SCHEMBL142480 0.81 LPL (0.62) TAAR1LPLLIPG
SCHEMBL15242107 0.81 HRH3 (0.58) HRH3TAAR1CHRNA7
SCHEMBL3440327 0.81 HRH3 (0.57) HRH3TAAR1CHRNA7KCNH2
SCHEMBL3046909 0.80 HRH3 (0.70) HRH3TAAR1CHRNA7KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394979-B2 Process for preparing cycloplatinated platinum complexes, platinum complexes prepared by this process and the use thereof RHEINISCHE-WESTFALISCHE TECHNISCHE HOCHSCHULE AACHEN (DE) 2013-03-12 US disclosed
US-20100267977-A1 METHOD FOR PRODUCING CYCLOPLATINIZED PLATINUM COMPLEXES, PLATINUM COMPLEXES PRODUCED BY SAID METHOD, AND THE USE THEREOF RHEINISCHE-WESTFALISCHE TECHNISCHE HOCHSCHULE AACHEN (DE) 2010-10-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100267977-A1 METHOD FOR PRODUCING CYCLOPLATINIZED PLATINUM COMPLEXES, PLATINUM COMPLEXES PRODUCED BY SAID METHOD, AND THE USE THEREOF THPO, MCL1, PPOX HRH3 3145/4885TAAR1 4519/4885LPL 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.