Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 4/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270322 | 1.00 | FBP1 (0.44) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL28341319 | 0.88 | FBP1 (0.44) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL28343819 | 0.88 | FBP1 (0.44) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL28341321 | 0.88 | FBP1 (0.44) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL1947929 | 0.84 | GABRA1 (0.53) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL30500145 | 0.84 | GABRA1 (0.53) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL1947930 | 0.84 | GABRA1 (0.53) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL11858720 | 0.79 | ABL1 (0.55) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL11846919 | 0.79 | MAPT (0.59) | FBP1ABL1EGFRABL2ALDH1A1 | |
| SCHEMBL11846922 | 0.79 | MAPT (0.59) | FBP1ABL1EGFRABL2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101489999-B | N- (l-alkyl-2- phenylethyl) -carboxamide derivatives and usethereof as fungicides | SYNGENTA LTD (GB) | 2012-07-04 | — | — | CN | disclosed |
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2011-08-25 | — | — | US | disclosed |
| CN-101489999-A | N- (l-alkyl-2- phenylethyl) -carboxamide derivatives and usethereof as fungicides | SYNGENTA LTD (CH) | 2009-07-22 | — | — | CN | disclosed |
| EP-2035374-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | Syngeta Participations AG (CH) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007141009-A1 | N- (L-ALKYL-2- PHENYLETHYL) -CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110207771-A1 | N-(L-ALKYL-2-PHENYLETHYL)-CARBOXAMIDE DERIVATIVES AND USE THEREOF AS FUNGICIDES | CYP1A1, CYP51A1, CYP2E1 | FBP1 1406/4885ABL1 716/4885EGFR 3321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.