Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | DDX3X | O00571 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 10/20 | 0.50 |
| ▸ | RAB9A | P51151 | 10/20 | 0.50 |
| ▸ | PKM | P14618 | 5/20 | 0.50 |
| ▸ | KLF5 | Q13887 | 3/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002089 | 0.90 | MEN1 (0.58) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL13058906 | 0.83 | MEN1 (0.62) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL3767781 | 0.81 | AKR1C3 (0.73) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL20685426 | 0.81 | RAB9A (0.64) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL17054445 | 0.80 | MEN1 (0.67) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL18473152 | 0.80 | MEN1 (0.58) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL3774292 | 0.79 | MEN1 (0.57) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL13058945 | 0.79 | MEN1 (0.57) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL20685429 | 0.78 | LMNA (0.73) | MEN1KMT2AAKR1C3DDX3XNPC1 | |
| SCHEMBL13002096 | 0.78 | MEN1 (0.56) | MEN1KMT2AAKR1C3DDX3XNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200369723-A1 | LLP2A-BISPHOSPHONATE CONJUGATES FOR OSTEOPOROSIS TREATMENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369723-A1 | LLP2A-BISPHOSPHONATE CONJUGATES FOR OSTEOPOROSIS TREATMENT | LCP1, BST2, ITGA2B | MEN1 1824/4885KMT2A 950/4885AKR1C3 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.