SCHEMBL2270403

SCHEMBL2270403

C=C([SiH3])c1ccccc1NC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.52
KDM4E B2RXH2 3/20 0.52
ATM Q13315 1/20 0.52
MAPT P10636 5/20 0.40
ALDH1A1 P00352 3/20 0.40
RECQL P46063 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
HPGD P15428 2/20 0.40
USP2 O75604 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TSHR P16473 2/20 0.37
IDO1 P14902 1/20 0.36
FABP3 P05413 1/20 0.35
FABP4 P15090 1/20 0.35
FABP5 Q01469 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
KMT2A Q03164 4/20 0.33
RAB9A P51151 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2104431 0.82 KDM4E (0.39) POLBKDM4EATMMAPTALDH1A1
SCHEMBL27276860 0.80 POLB (0.53) POLBKDM4EATMMAPTALDH1A1
SCHEMBL8574363 0.80 POLB (0.53) POLBKDM4EATMMAPTALDH1A1
Hydrochloric Acid SCHEMBL28447296 0.78 POLB (0.52) POLBKDM4EATMMAPTALDH1A1
SCHEMBL14431763 0.78 KDM4E (0.52) POLBKDM4EATMMAPTALDH1A1
SCHEMBL2274708 0.78 IDO1 (0.42) POLBKDM4EMAPTALDH1A1RECQL
SCHEMBL2495680 0.77 POLB (0.59) POLBKDM4EATMMAPTALDH1A1
SCHEMBL20274421 0.75 KDM4E (0.48) POLBKDM4EATMMAPTALDH1A1
SCHEMBL30343763 0.75 POLB (0.48) POLBKDM4EATMMAPTALDH1A1
SCHEMBL29345253 0.74 POLB (0.47) POLBKDM4EATMMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8404584-B2 Method of manufacturing semiconductor device FUJITSU LIMITED (JP) 2013-03-26 US disclosed
US-20110207319-A1 METHOD OF MANUFACTURING SEMICONDUCTOR DEVICE FUJITSU LIMITED (JP) 2011-08-25 US disclosed