⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15251465 | 1.00 | — | — | |
| SCHEMBL22703928 | 0.90 | — | — | |
| SCHEMBL24638658 | 0.85 | — | — | |
| SCHEMBL18359139 | 0.84 | SAT1 (0.31) | — | |
| SCHEMBL24919619 | 0.80 | SIGMAR1 (0.36) | — | |
| SCHEMBL2443414 | 0.78 | NOS3 (0.33) | — | |
| SCHEMBL23637950 | 0.78 | — | — | |
| SCHEMBL22275157 | 0.78 | SAT1 (0.38) | — | |
| SCHEMBL18721054 | 0.78 | SAT1 (0.38) | — | |
| SCHEMBL7898141 | 0.78 | SAT1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020233512-A1 | AROMATIC AMINE AR AND BET TARGETING PROTEIN DEGRADATION CHIMERA COMPOUND AND USE | 成都海创药业有限公司 (CN) | 2020-11-26 | — | — | WO | disclosed |